Below is a list of toxic agents used in industry and potentially toxic to peripheral nerves. This list is not exhaustive. – Acrylamide (flocculating agent) causes sensory damage to large nerves with sensory ataxia. –
Installation in a few hours: Mainly vasculitis (polyarteritis nodosa) The picture is more of a multineuritis with multiple radicular or truncal involvement. Installation in a few days: – Guillain-Barrè syndrome and its variants. – Neuropathy
The main drugs that can cause peripheral neuropathy are: – Periwinkle alkaloids: Vinblastine, Vincristine, Vindesine, Vinorelbine. -Almitrine – Amiodarone – Nucleoside analogues (didanosine, zalcitabine, stavudine, etc.) – Chloroquine – Cimetidine – Cisplatin – Dapsone –